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Rise of kidney disease partly due to inherited West African gene, Study finds

A study conducted by Professor Vincent Boima has found that genetic factors may be playing a major role in the increasing prevalence of kidney disease in Ghana and across West Africa.

According to the study, certain genetic traits common among people of West African descent could increase vulnerability to chronic kidney disease (CKD), particularly when combined with conditions such as hypertension, infections and poor living conditions.

Prof Boima disclosed the findings during his inaugural lecture at the University of Ghana on Thursday under the theme, “From Genes to Mind: Holistic Pathways to Precision Kidney Care for Africa.”

He explained that a gene known as APOL1, which is prevalent among many West Africans, has been associated with a higher risk of kidney-related illnesses.

“People with this gene are more likely to develop kidney disease, especially when other factors such as infections, high blood pressure, or poor living conditions are present,” he said.

The professor warned that kidney disease is becoming an increasing public health concern in Ghana, noting that many patients are diagnosed only at advanced stages when treatment options are limited and expensive.

He added that the condition disproportionately affects younger and economically productive populations, raising concerns about the broader social and economic impact on families and the country.

Prof Boima stressed the need for more African-led medical research to improve understanding of how genetics influences kidney disease within the region.

“This will help doctors provide more accurate and effective treatment for patients,” he stated.

He also called for expanded screening and early detection programmes to help identify kidney disease before it progresses to severe stages.

According to him, genetic information should be applied responsibly to improve healthcare outcomes without creating fear or discrimination.

Prof Boima further urged government and health authorities to strengthen healthcare systems, improve access to treatment, and intensify public education on kidney disease prevention and management.

He encouraged the public to adopt healthier lifestyles, including regular medical check-ups, blood pressure control and balanced diets, to reduce the risk of kidney complications.

The lecture, held at the Great Hall of the University of Ghana, formed part of ongoing academic discussions aimed at addressing the growing burden of kidney disease in Ghana and across Africa.

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